Hypertension control at a nephrology clinic at Jordan university hospital

To determine the degree of control of hypertension in hypertensive patients attending the nephrology clinic. A cross sectional study carried out by examining the records of patients with hypertension attending the nephrology clinic. There were 335 subjects included with mean age of 58.8 +/- 13.4 years and 189 [56.4%] were women. The mean systolic BP was131 +/- 13 and mean diastolic BP was 79 +/- 7. Two hundred seventy three subjects [81.5%] had BP

Comparison of creatinine clearance estimates with routine measured clearance in adult Jordanians

To determine the correlation between endogenous creatinine clearance, the Modification of Diet in Renal Disease and Cockcroft-Gault equations, and to examine agreement between these methods. Creatinine clearance measured by 24-hour urine creatinine in patients with chronic kidney disease was compared with estimated clearance using the Cockcroft-Gault and Modification of Diet in Renal Disease equations. Correlation, regression analysis, limits of agreement and concordance analysis were used. There was a positive correlation between both the Cockroft-Gault [r=0.931, p<0.001] and the Modification of Diet in Renal Disease [r=0.741, p<0.001] equations with creatinine clearance; the former being statistically superior [P=0.0073] comparing the correlation coefficients. Using Bland-Altman method, there was better agreement with the Cockcroft-Gault formula where the limits of agreement were [-10.1 to + 11.2] compared with [-22.8 to + 18.5] for the Modification of Diet in Renal Disease. Concordance analysis showed a concordance correlation coefficient of 0.938 [95% CI, 0.89-0.97] for Cockroft-Gault and 0.713 [95% CI, 0.55-0.82] for Modification of Diet in Renal Disease. Pearson p coefficient [precision] and bias correlation factor Cb [accuracy] of Cockcroft-Gault were 0.939, 0.998 and of Modification of Diet in Renal Disease they were 0.713 and 0.947, respectively. In Jordanian patients, the Cockcroft-Gault equation had a superior performance in the estimate of creatinine clearance compared to the Modification of Diet in Renal Disease equation. Further studies to evaluate these formulae with larger number of patients and using a gold standard method are needed. In the meantime, we suggest using the Cockcroft-Gault equation in patients with a moderate-to-severe chronic renal failure

Bilateral renal angiomyolipoma with bilateral sarcomatous change

A 54-year-old man presented to the nephrology clinic with three months history of hematuria, weight loss and loss of appetite. Radiological and pathological investigations pointed to the diagnosis of multiple bilateral renal angiomyolipomas with bilateral high grade sarcomatuos transformation and lung metastasis, and with no manifestations of tuberous sclerosis. This is the first reported case of bilateral renal angiomyolipomas with multiple sarcomatous changes